Sibutramine genuine powder

"Sibutramine The chemical formula C17H26ClN is an appetite inhibitor that acts on the central nervous system. It can be used as an oral weight loss drug in medicine. It is usually made of sibutramine hydrochloride (C17H26ClN·HCl·H2O).1.Name:Sibutramine
2.Appearance:White crystalline powder
3.Specification:98%
4.CAS No.:C17H26ClN
5.Molecular Formula:C22H30N6O4S
6.Molecular Weight:474.58
7.Payment Method:T/T Alipay
8.Certificates: FDA,Organic,Kosher, ISO, HALAL, HACCP, GMP
9.Transport Package:1kg Aluminum Foil Bag/25kg Drum
10.Factory situation:One Factories & Three production lines.GMP standard workshop & two independent laboratories.
11.Storage method:Dry and cool place
12.MOQ:1KG
13.Service: powder"
Product Description

Introduction to Sibutramine Powder Products of Guangzhou Jianbei Biotechnology Co., Ltd

Company Profile
Guangzhou Jianbei Biotechnology Co., Ltd. is a leading supplier of Sibutramine genuine powder raw materials in China, focusing on product quality, corporate reputation, and service. The company provides one-stop service to ensure sufficient product inventory and fair prices, creating lasting cooperation value for customers.

 
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Company and Product Introduction

Company

Company

Product Introduction

Product description

Product Name: Sibutramine genuine powder
Appearance: White crystalline powder, no lumps, with a unique pungent odor
Application Fields and Core Functions
1. Scientific weight loss
By being rich in dietary fiber to enhance satiety and reduce calorie intake; L-carnitine helps with fat metabolism. Through clinical verification, this product can effectively assist in weight loss of 0.5-1 kg per day.
2. Intestinal regulation
Containing water-soluble dietary fiber, it helps promote intestinal peristalsis and improve constipation problems. Each pack contains 6.5 grams of dietary fiber, which meets 25% of the daily needs of adults.
3. Nutritional supplementation
Specially added collagen peptides and vitamin B family ensure the maintenance of skin elasticity and radiance during weight loss, while relieving fatigue and preventing malnutrition.

Comparison before and after using sibutramine powder

Comparison before and after using sibutramine powder

What is it Sibutramine genuine powder 

Sibutramine genuine powder (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of obesity. It is a centrally acting stimulant chemically related to amphetamines. Sibutramine is classified as a Schedule IV controlled substance in the United States. In October 2010, Sibutramine was withdrawn from Canadian and U.S. markets due to concerns that the drug increases the risk of heart attack and stroke in patients with a history of heart disease.Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.

Sibutramine genuine powder is a synthetic drug originally developed by Novartis in Switzerland, primarily used for the treatment of obesity. It belongs to a selective serotonin and norepinephrine reuptake inhibitor (SNRI) that can affect neurotransmitter levels in the brain, thereby regulating appetite and energy expenditure. Although there is a significant weight loss effect on some patients in the short term,

Sibutramine genuine powder 

Sibutramine genuine powder Its function

is a medication widely used to treat obesity. It reduces appetite and increases satiety by inhibiting the reuptake of neurotransmitters, thereby helping patients lose weight.

developed by Knoll, Inc., Germany, was first launched in the United States in April 1998. As a norepinephrine and 5-HT reuptake inhibitor, sibutramine acts primarily through its metabolites. It can increase physiological satiety, reduce appetite, induce heat production and increase energy consumption by inhibiting the reuptake of monoamine information transmission factors such as 5-HT and norepinephrine, decreased fat accumulation. Obesity Treatment for diet control, exercise failure to reduce and control weight.

Sibutramine genuine powder 

p-chlorophenylacetonitrile, KOH and acetonitrile were mixed, and 1,3-= bromopropane was slowly added dropwise at 25 ° C. For reaction. After completion of the reaction, distilled water was added, followed by extraction with hexyl acetate. The extract was washed with water, saturated brine, and dried. The compound was obtained by filtration, concentration under reduced pressure and distillation. Magnesium tablets are dissolved in THF, Dropwise adding isobutyl bromide, then reacting, slowly dropping the THF solution of the compound obtained from the surface, refluxing, and stirring the treated compound with formic acid and formaldehyde solution, the reaction was slowly added to a crushed ice solution of sodium hydroxide with stirring, and then extracted with ether. The extract was washed with saturated brine and water and dried. Filtration and concentration of the filtrate gave sibutramine.

factory

Sibutramine genuine powder Drug use

1.5-HT reuptake inhibitors are used for the treatment of obesity.
2. As an inhibitor of norepinephrine and 5-HT reuptake, sibutramine mainly exerts its effects through its metabolites. It increases physiological satiety, reduces appetite, induces thermogenesis, increases energy expenditure, and reduces fat accumulation by inhibiting the reuptake of monoamine signaling factors such as 5-HT and norepinephrine by cells. Used for the treatment of obesity that cannot be reduced through diet control, exercise, and weight control.
Pharmacological action
Sibutramine genuine powder is a non amphetamine type appetite suppressant and also has antidepressant properties. Sibutramine mainly acts through its secondary (M1) and primary (M2) amine metabolites, and its mechanism of action is to inhibit the reuptake of norepinephrine, serotonin, and dopamine, increase satiety, and accelerate energy expenditure, while having no significant effect on the release of norepinephrine, serotonin, and dopamine. The study also showed that sibutramine and its amine active metabolites have no significant anticholinergic, antihistamine, or monoamine oxidase inhibitory effects [6].

Sibutramine genuine powder 

 

COA (Product Analysis Report)

Product Name: Jianbei Brand Compound Plant Sibutramine genuine powder
Batch number: JBSF20231001
Testing items and results: This product contains components such as L-carnitine, dietary fiber, collagen peptides, and vitamin B family. The microbiological indicators and heavy metal content meet the standard requirements, and the product has a shelf life of 24 months.
The quality standards and production standards of this product comply with relevant national standards.

TEST 
SPECIFICATION 
RESULT
Description  
White or almost white slightly hygroscopic crystalline powder.
Conform
Solubility  
Slightly soluble in water and in methanol, practically insoluble in hexane.
   Complies  
Identification by IR  
The Infrared absorption spectrum of sample is concordant with the spectrum of Sildenafil citrate RS 
   Complies  
Water content by (KF)
Not more than 2.5 % w/w   ≤2.5% w/w
1.49 % w/w
Residue on ignition
Not more than 0.1% w/w    ≤1.0% w/w
0.04 % w/w
Organic impurities by HPLC
Sildenafil related compound A
Not more than  0.3 %     ≤0.30 %
BDL
Any other unspecified individual impurity
Not more than  0.10 %   ≤0.10 %
BDL
Total unspecified impurities
Not more than  0.3 %    ≤0.30 %
BDL
Total impurities  
Not more than  0.5 %     ≤0.30 %
BDL
Assay by HPLC (On anhydrous and solvent free basis) 
Not less than 98.0% w/w to not more than
102.0 % w/w                   98.0%~102.0% w/w
99.00 % w/w

 

Packaging and Shipping

1. Packaging specifications
The standard packaging options include aluminum foil bags and transparent food bags for 10 grams, 1 kilogram, 5 kilograms, 10 kilograms, and 25 kilograms. All products are packaged in cardboard boxes.
2. Transportation mode
Domestic orders default to using express delivery services, with an estimated delivery time of 3 to 5 days. Bulk orders are delivered through Debon Logistics and enjoy free shipping services. For cross-border transportation, we offer options for sea freight (expected to arrive in 45 days) and air freight (expected to arrive in 7 days), and will provide necessary customs clearance documents.

Packaging and Shipping

Why choose us

Provide comprehensive pre-sales and after-sales services, including product consultation, technical support, logistics tracking, etc., to ensure that customers have no worries during the cooperation process. At the same time, we can also provide packaging and transportation solutions for Sibutramine genuine powder according to customer needs, to meet the differentiated needs of different markets

Core values: Direct supply from the source factory+controllable quality+flexible customization, helping customers enter the slimming market with low risk and high profit.
Collaboration support:
Contact Information
Business Manager: Manager Li  WATHSAPP +85362906527
Email: h33727868@gmail.com 
Factory Address: No. 142 Wushan Road, Tianhe District, Guangzhou, Guangdong Province, China

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